Frequently Asked Questions

Should you have any question about GPRO, check this section in which we provide answer to frequently asked questions. If you do not find the answer you need in this section, please check the manual of GPRO or contact us directly.

What are the GPRO system requirements?

GPRO is a Java application that runs on all personal computers (PCs) and workstations as standalone software. The program is distributed as an installer for Windows XP/Vista/7 (32 bit and 64 bit), a self-extracting disk image for Mac OS X 10.5 or later (64 bit), and a compressed tarball archive for Linux 2.6 kernel series or later (32 bit and 64 bit). We however recommend the following combinations.

Microsoft Windows

  • Windows XP/Vista/7
  • Intel Pentium 4 1.5 GHz or Athlon XP 1500+ processor or higher
  • 2 GB RAM


  • Linux distributions
  • Intel Pentium 4 1.5 GHz or Athlon XP 1500+ processor or higher
  • 2 GB RAM

Apple Mac OS X

  • Mac OS X 10.5 or later
  • Intel Core Duo processor or higher
  • 2 GB RAM

All systems require Java 6 or later. The latest version can be downloaded from the following URL: Please note that for projects containing a large number of sequences, a minimum of 4 GB of RAM is recommended for optimum performance.

May I lose my data if I upgrade or re-install GPRO?

No, your data are stored in any folder in any place of your computer you link to GPRO as main Directory. This means that the directory is independent from the GPRO installation. Anyway, If you usually store the Directory of data in the folder of your PC where you installed GPRO we suggest you to make a backup of your data. This is just in case because the installation or upgrade of GPRO does not remove any previously existent folder in your computer.

About the copyright and licensing

Licensing of GPRO is subject to a commercial and private source agreement that should be accepted during installation of the tool in your PC. This agreement allows unrestricted use of the tool for academic and industrial research and services (online or to third parties) but does not permit the sale, rent, re-distribution, reverse engineering, decompiling, disassembly, or otherwise translation or analysis of any source code of the software, underlying ideas, algorithms or programming by any means without our explicit authorization.

Why the license of GPRO is annual?

This is because the licensing of GPRO includes not only the use of the executable software but also accession to the services and user account provided by a pipeline installed on a high-end remote cluster within the Gypsy database (GyDB) for running intensive computational jobs from your PC. In short, GPRO is a software coupled with a computational server.

If my GPRO license expires might I lose my data or I will be able to launch GPRO again?

No worries, the executable GPRO works even if your GPRO license expires. What follows to the license expiration is the inactivation of the pipeline services associated to the tool. This means that you can keep running the commands and functions of GPRO (and of course maintain and display your data) with the exception of those that GPRO runs via pipeline. To re-activate these services you must to renew again the license.

Should I have two computers do I have to buy two personal licenses for GPRO?

No, if you acquired a single user license you can use it on up to three computers, provided that no one else uses your license and you do not use your license on more than one computer simultaneously.

If I belong to a department including other researchers interested in GPRO, can I buy a multi-license?

Yes you only need to select the distinct options of multi-license available in the form you must to fill when acquiring your license.

What if I find a bug in my GPRO license?

GPRO has been satisfactorily tested but should your license prove defective, warranty assistance is provided via the technical support service. You can access this service via the "suggestions and bugs" utility implemented within the "Help" tab of the main GPRO menu or by accessing our technical support service.

Why do I see "#####" values in my BLAST report file when editing in Microsoft Excel?

This is because Excel tries to apply a built-in number format to the cell, based on the characteristics of the number. Pound signs indicate that Excel has encountered a formatting problem with that values. To see the actual values with the right format try the following:

  • Select the column to be formatted.
  • Right-click on the column.
  • Select "Format cells...".
  • Then, select "Scientific" or "Text" depending on the data type contained in the column.

What sould I do if I get an "A Java Runtime Environment (JRE) or Java Development Kit (JDK) must be available in order to run GPRO" error message

This error happens when Java executable PATH has not been properly set on system's environment variables.

Instructions for Windows systems:

  • Right click “My Computer” icon
  • Choose “Properties” from context menu
  • Click “Advanced” tab (“Advanced system settings” link in Vista and 7)

  • In the Edit windows, modify PATH by adding the location of the class to the value for PATH. If you do not have the item PATH, you may select to add a new variable and add PATH as the name and the location of the class as the value.

  • Run GPRO